Mass Spectrometry Platform for Natural Product Analysis

Typical Workflow of
Natural Products
Discovery

1. 1 Source Sampling
2. 2 Extraction
3. 3 Measuring
4. 4 Spectrum Analysis

1. 1. Source Sampling

   Preparing a sample of a natural product as a component extraction target. Since natural products may exhibit different characteristics depending on various conditions such as vegetation, environment, etc., it is of utmost importance to prepare well-selected samples. For high purity extraction of active ingredients, impurity removal work must be preceded.

2. 2. Extraction

   Extracting raw material from the natural product to be extracted. As raw material, it is necessary to prepare the appropriate amount according to the analysis method and conditions, and the result may change depending on the purity of the raw material. Therefore, purity control at the extraction stage is very crucial.

3. 3. Measuring

   Analyzing the extracted raw materials using MS/MS. In order to utilize SnaPeaks platform, data should be prepared in mzML format or MGF format provided by most mass spectrometers.
   The result may be different according to the resolution of the instrument utilized.

4. 4. Spectrum Analysis

   Interpreting mass spectrometric data using SnaPeaks platform. It provides ingredient analysis result of raw material through comparison with the spectrum DB of natural products owned by SnaPeaks. It also provides general information and the metadata of spectrum.